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Hepatitis C

 

Intro
Hepatitis C is one of three common viral infections of your liver (Hepatitis A and Hepatitis B are the others), and until relatively recently we did not even know it existed. There are approximately 35,000 new cases of hepatitis C in the U.S. each year, and only about one-third of these produce symptoms. Hepatitis C is more dangerous, though thankfully far less common, than Hepatitis A or B because it usually develops into a chronic infection –- even in people with normal immune systems. It can lead to cirrhosis (scarring), liver cancer, liver failure and death. Unfortunately, no vaccine protects you from this disease. Of late, there has been buzz about hepatitis C, leaving many people worried about possible infection. It still, however, remains a relatively rare disease and may not even be one-tenth as common as hepatitis B.

What is it?
Hepatitis C is a viral infection that attacks your liver. Doctors still do not fully understand various aspects of this infection. We do know that many people don’t know they have (or had) the infection, until a blood test turns up positive. Hepatitis C can also produce a severe and life threatening infection which can lead to liver failure and death. The real danger of hepatitis C comes from your body’s inability to rid itself of the infection. So, in 90 percent of people with normal immune systems, hepatitis C becomes chronic, and in about 20 percent of these cases, progress to cirrhosis. Hepatitis C infection also increases your chances for liver cancer (hepatoma), liver failure and death. Hepatitis C is even more dangerous for people with HIV and other immune compromising conditions. They almost always develop chronic hepatitis with more rapid deterioration of their liver.

Symptoms
Hepatitis C symptoms are extremely variable, both in severity and duration. Some people are deathly ill while many others don’t even realize they are sick. The most common symptom is profound fatigue –- some feel that they can’t even get out of bed. Other common symptoms include nausea and vomiting (generally worsening as the day progresses), loss of appetite, fever, muscle aches and dull upper abdominal discomfort. Most people develop jaundice (they turn a lovely shade of yellow, most noticeably in the whites of their eyes). This results from your liver’s inability to process bile. Your urine darkens and your stool can turn to a sand color.

Diagnosis
Many times your doctor first notices that your eyes and skin have taken on a yellow cast. A blood test will detect liver inflammation (enzymes from diseased liver cells spill into your blood and are elevated over normal levels). Now your doctor knows you have hepatitis, but doesn’t know what kind. Different blood tests check for parts of the hepatitis C virus or antibodies that your body manufactures to fight it. If either of these is present your doctor knows that you have hepatitis C. Hepatitis C virus particles and antibodies differ from those found with other types of hepatitis.

How do you get it?
Hepatitis C is most often spread through contaminated blood, but you don’t need a transfusion to catch it. A microscopic amount of infected blood may be enough to give you the infection. Shared needles (even tattooing needles), razors, toothbrushes and sex toys can all pass the virus between individuals. People on kidney dialysis and who have received organ transplants before 1992 are at increased risk for hepatitis C. The Centers for Disease Control and Prevention (CDC) classifies hepatitis C as a sexually transmitted disease in men who have sex with men, but it is not clear how it is spread. Although the virus is probably in semen, it appears difficult to catch from unprotected anal or vaginal sex. Hepatitis C has not been shown to pass through unprotected oral sex.

How to treat it?
There are no medications designed specifically to treat acute hepatitis. Treatment is generally described as "supportive," with the key components being rest, good nutrition, and careful monitoring to be sure your liver recovers. Nausea is common with hepatitis and because it often worsens as the day progresses, most doctors recommend that you eat your bigger meals earlier. Medication can help those with severe nausea. Hospitalization is rare, but occasionally necessary if you cannot take in adequate food and water or if you are too weak to remain at home.

Avoid all alcohol and drugs, which further tax your liver, until you are fully recovered -- your doctor, not your symptoms, determine whether or not you are recovered. See your doctor regularly to monitor your liver function and nutritional status.

Your doctor may recommend a liver biopsy if you are interested in pursuing treatment with interferon (your doctor may prescribe a combination therapy of interferon and ribaviron). A pretreatment biospsy will assess the progression of inflammation and fibrosis in your liver. Some doctors feel that if your liver function tests and platelets are normal, however, and you're not planning to take interferon, then there is little reason to have a biospy.

You don't need to isolate yourself if you have hepatitis C, just avoid anything that would put your blood in contact with others, including shared razors, needles and toothbrushes or improperly disposed menstrual pads… you get the idea.

Anyone who has had hepatitis C should be vaccinated against hepatitis A and B. Either of these infections coupled with hepatitis C could seriously destroy your liver.

Prevention
Fortunately doctors now have tests that check for hepatitis C virus in blood transfusions and this has drastically reduced your risk. There is no vaccine available yet to protect you from hepatitis C. Never share needles, razors, toothbrushes, sex toys or anything that can transmit even a minute amount of contaminated blood. If you have hepatitis C, you may be contagious before you know you have the infection and after you think you’re over it.

Incubation period
If you do get symptoms, they usually appear from two weeks to six months after exposure. Keep in mind that many infected people don't develop any symptoms and can spread this disease unknowingly.

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